Every day, approximately 14,000 people around the world are newly infected with HIV; of these, almost half are women. Even as they encounter increased risk, many women have minimal control over HIV/STD prevention decisions. Microbicides could change this reality. Microbicides are products applied directly to the vagina or rectum that minimize the risk of transmitting STDs. Microbicides containing contraceptive agents may also facilitate fertility regulation.
Microbicides, the compounds and formulations that can prevent transmission of sexually transmitted diseases (STDs)/HIV are being pursued actively as a promising AIDS intervention. Microbicides for sexually transmitted diseases, are pharmacologic agents and chemical substances that are capable of killing or destroying certain microorganisms that commonly cause human infection, for example the human immunodeficiency virus. Microbicides are a diverse group of chemical compounds that exert their activity by a variety of different mechanisms of action.
Microbicides can be formulated in various delivery systems, including gels, creams, lotions, aerosol sprays, tablets or films that must be used near the time of sexual intercourse, or as sponges, vaginal rings or other devices that release the active ingredient(s) over a longer period of time.Some of these agents are being developed for vaginal application, and for rectal use by those who engage in anal sex.
Several factors, including changes in the physiology of the cervix and vagina with age and menstrual cycle, intercourse, as well as leakage of the formulation from the vagina may affect their design, development, and performance. Selection and development of optimal microbicide delivery systems (gel/cream, pessary, film, tablet, foam, etc.), their inactive ingredients, manufacturing details, and packaging system are dependent on the properties of active drug, or their preformulation parameters (PP).
The PP of the active dug substance needs to be evaluated in initial stages of drug discovery and development so that the most suitable delivery system can be selected. Some PP of microbicide agents include physical state, organoleptic properties (color, odor, appearance, taste, etc.), molecular weight, aqueous solubility, hygroscopicity, acidity/alkalinity, permeability and absorption characteristics, stability in solid/solution state, and inherent bioadhesiveness. Thus, a well-coordinated, planned, and implemented preformulation program can help in not only accelerating microbicide formulation development, but also to minimize unforeseen failures in subsequent stages of the development.
Yes yes & yes many cancers & like diseases like HIV/AIDS, HSV/HERPES, and many organ related diseases are cured this days with herbal remedies & more herbal treatments are being discovered all the time. More anticancer & antiviral herbal drugs are in clinical trials this days than ever before and promising herbalist like Dr Utu all thanks to him. I do hear of many people he has helped cured their diseases using African natural Herbs & Roots. I'm Paul G. From Australia a father of four which include 3 girls and a boy. My boss is more than a father to me, he assist my family even financially. He completely lost himself when he was diagnosed of kidney stone & to make matter worst he started noticing his first outbreak. Ever since his kidney stone issues, he keep having herpes outbreak on any little fever. He's my boss and the only way I can pay him is to help his situation. At first I doubted Dr Utu, but in a case of life & death as this am left with only a choice. I contacted Dr Utu to give him a try. He sent herbal meds to my boss that completely flushed out the stone in his kidney. He completely cured my boss of kidney stone and herpes virus using African herbs. I also prescribed this herbal cure for a colleague with HIV and he was completely cured. Dr Utu is health future. Through me Dr Utu have completely cured; herpes, hiv, cancers, kidney stone. I think it pays to be good because you never know who might pay you back in future. So my knowledge on this is what I share. For the sick, trying herbal meds will tell you the different. Reach Dr Utu on his email; drutuherbalcure@gmail.com
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ReplyDeleteIt took almost one year for my first real outbreak but it was the hardest thing in the world to get along with. I felt so unwanted and dirty. I tried many formulas, suggestions, methods to get rid of it permanently. Booked appointment with many doctors, professionals, even religiously until I started getting away spiritually and still it won't go. The worst is my outbreaks occurs within short period and take as long as even weeks to go away. I was at last placed on antiviral treatment which is a good treatment but for how long? I prayed every four times a day for God to cure me miraculously or direct me to cure because I know there is. During outbreaks I thought it's the end of the world but it's not, with time I will become normal again. I started trying fruits and herbs, take herbal produced, and with time became very interested in herbs. I read blogs, websites, and comments on herbs and built a stronger hope. I saw comments and decided to try Dr Utu African Traditional Herbal meds. I know of one mr Brown who was HIV and now brags he was cured of HIV with Dr Utu traditional meds but never give it a thought because I believed HIV already has a cure and never think it through or make a research. And for herpes my doctor told me that there is no known cure. When I saw testimonies of his Herpes cure on sites. I copied his contact drutuherbalcure@gmail.com. I showed it to brown who confirmed it was Dr Utu contact. I contacted him immediately and he also prepared and sent me herbal herpes meds through DHL. Right after getting this traditional meds I followed the prescription cautiously and withing days I started noticing rapid change and I know within me it's the cure. I used it for up to two weeks and when my test result was out not only did this herbal meds cure me but boost my immune and I feel real and free. Dr Utu African Traditional meds have successfully cured Herpes, Warts, HIV, Cancers, Kidney Stone, Asthma, most importantly this traditional meds boost immune and have no after effect.
I am deeply concerned about the still increase in population of people living with HSV, HIV, CANCERS, HEPATITIS, STROKES in our society today because of ignorance, to be Frank all this big names are grammars. I saw comments of people DR UTU helped get rid of their diseases, with the increase in population of people living with various diseases and myself as a beneficiary to DR UTU traditional cure I thought I too should reach the world via comment. Many People believed traditional herbs are so primitive and some are even shy to purchase it in public. Some went as far as trashing the legendary name of herbal medicine hiding its numerous advantages and let publicly it disadvantage and yet makes it look big, all this are just for pharmaceutical gain. All pharmaceutical cure are derived from existing traditional herbal cure from ages.
ReplyDeleteYes! I'm here to tell the world the actual FACT! which is; there is herbal cure for herpes, Ebola, HIV, cancers, hepatitis, ulcers, asthma, pile, diabetes and many big names of diseases. all my career I've lived my life believing and making research on this, till I confirmed it four years ago. Since four years ago and till today I still say yes! That among many real traditional herbalist Dr Nze Utu Njoku @ (drutuherbalcure) cures this diseases using African traditional herbs. After he cured me four years ago of genital herpes, ever since then I worked with him distance never a barrier, I'm a living witness to this. And I have directed both genital and oral herpes patients to him and they are permanently cured. I'm Ethan Oliver from Australia and also a herbal dealer and lover. I'm also a researcher on herbs for good health. Which also include Africa traditional herbal treatment, I support Herbal treatment, cure and vaccines. My view is based on my extensive research over a very long period of time, and my conclusion is, there is cure to all natural diseases including HSV, HIV, CANCERS, DIABETES, using the right medications with the right herbalist. Are you herpes positive and permanently want get rid of this disease or any of this big name diseases don't be scared to save yourself, contact Dr Utu for permanent herbal cure. Be bold and smart Don't be fooled by selfish people who say, cure is impossible.
Dr UTU e-mail , 'drutuherbalcure@gmail.com'