Sunday, February 19, 2012

Microbicides and women




Microbicides are substances capable of reducing the transmission of HIV and other sexually transmitted pathogens when applied vaginally.Evidence from many settings strongly suggests that many women will find microbicides easier to use than condoms and that they can be used when condom use is not possible. This has raised the concern that women might abandon condoms in favour of microbicides. Indeed, the fear of 'condom migration' has been a major barrier to the widespread endorsement of microbicides as a potential method of HIV prevention.

Despite such high HIV-efficacy, there is substantial evidence that in many settings levels of consistent condom use is low, especially within primary partnerships. Studies show that even after directed intervention, the percentage of couples that achieve consistent condom use seldom exceeds 20-30%, except where individuals know that one partner is HIV infected. Success in increasing the consistency of condom use has been greatest among sex workers and other vulnerable groups, but even here, many sex workers do not use condoms consistently with their non-commercial, primary partners.

Even when condoms are used consistently they may be used incorrectly. The immense gap between the numbers requiring protection and those using condoms consistently and correctly could potentially be filled by microbicides.

With AIDS vaccine efforts at an impasse, microbicides -- virus-blocking gels inserted into the vagina before sexual intercourse -- have risen from their own string of setbacks to once again offer hope of preventing HIV infections, at least in women.

Identifying a microbicide that works even partially could have a huge effect. Almost half of the more than 33 million people living with HIV worldwide are women; in sub-Saharan Africa, the figure is 60%.Abstinence and condoms have been the only proven ways to prevent or reduce the spread of HIV among adults. Circumcision lowers the risk for men, and already-existing AIDS drugs are used prophylactically to reduce mother-to-child transmission during birth or breast-feeding.

Safer sex is not only for the prevention of new HIV infections. For people living with HIV (HIV+), safer sex is important because it can prevent infection with other STDs that can weaken the immune system. If both people are HIV+, safer sex can also reduce the possibility of getting infected with another strain of HIV that is resistant to the drug regimen you are taking.

Receptive vaginal-penile sex, or heterosexual intercourse, is considered a high-risk activity. It is also considered the most common way that HIV is spread worldwide. While it is high risk for both women and men, HIV+ men are much more likely to spread infection to women than HIV+ women are to infect men.
To make vaginal-penile sex even safer, consider using lubricant (‘lube'). Lube can prevent the condom from breaking and also helps prevent small cuts or tears in the vagina and on the penis during penetration. Lube is good for un-lubricated condoms as well as ones that come already lubricated; sometimes the lubrication on the condoms is not enough.

When using latex condoms, use only water- or silicone-based lube. Do not use oil-based lubes like Vaseline, Crisco, shea butter, or baby oil with latex condoms because they weaken the condom and make it more likely to break. Silicone-based lube will last longer than water-based lube. Lube can also make the condom feel better.

In addition, there has been controversy over lubricants that contain nonoxynol-9, a spermicide that is added to some products. Recent studies by the CDC, the World Health Organization, and the Population Council of New York have each demonstrated that hundreds of epithelial cells, which provide a protective membrane in the anus, were stripped away by products containing N-9.

Originally, N-9 was thought to help prevent HIV, because it killed the virus in a test tube, but now it's been documented that N-9 washes away the protective cells and might actually increase the risk of infection.
Due to public pressure, all lubricant manufacturers agreed to stop making lube with nonoxynol-9.

Microbicides might also prevent infection during anal intercourse, although most studies have focused on vaginal transmission.

2 comments:

  1. Yes yes & yes many cancers & like diseases like HIV/AIDS, HSV/HERPES, and many organ related diseases are cured this days with herbal remedies & more herbal treatments are being discovered all the time. More anticancer & antiviral herbal drugs are in clinical trials this days than ever before and promising herbalist like Dr Utu all thanks to him. I do hear of many people he has helped cured their diseases using African natural Herbs & Roots. I'm Paul G. From Australia a father of four which include 3 girls and a boy. My boss is more than a father to me, he assist my family even financially. He completely lost himself when he was diagnosed of kidney stone & to make matter worst he started noticing his first outbreak. Ever since his kidney stone issues, he keep having herpes outbreak on any little fever. He's my boss and the only way I can pay him is to help his situation. At first I doubted Dr Utu, but in a case of life & death as this am left with only a choice. I contacted Dr Utu to give him a try. He sent herbal meds to my boss that completely flushed out the stone in his kidney. He completely cured my boss of kidney stone and herpes virus using African herbs. I also prescribed this herbal cure for a colleague with HIV and he was completely cured. Dr Utu is health future. Through me Dr Utu have completely cured; herpes, hiv, cancers, kidney stone. I think it pays to be good because you never know who might pay you back in future. So my knowledge on this is what I share. For the sick, trying herbal meds will tell you the different. Reach Dr Utu on his email; drutuherbalcure@gmail.com

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  2. It took almost one year for my first real outbreak but it was the hardest thing in the world to get along with. I felt so unwanted and dirty. I tried many formulas, suggestions, methods to get rid of it permanently. Booked appointment with many doctors, professionals, even religiously until I started getting away spiritually and still it won't go. The worst is my outbreaks occurs within short period and take as long as even weeks to go away. I was at last placed on antiviral treatment which is a good treatment but for how long? I prayed every four times a day for God to cure me miraculously or direct me to cure because I know there is. During outbreaks I thought it's the end of the world but it's not, with time I will become normal again. I started trying fruits and herbs, take herbal produced, and with time became very interested in herbs. I read blogs, websites, and comments on herbs and built a stronger hope. I saw comments and decided to try Dr Utu African Traditional Herbal meds. I know of one mr Brown who was HIV and now brags he was cured of HIV with Dr Utu traditional meds but never give it a thought because I believed HIV already has a cure and never think it through or make a research. And for herpes my doctor told me that there is no known cure. When I saw testimonies of his Herpes cure on sites. I copied his contact d r u t u h e r b a l c u r e @ g m a i l . c o m.
    I showed it to brown who confirmed it was Dr Utu contact. I contacted him immediately and he also prepared and sent me herbal herpes meds through DHL. Right after getting this traditional meds I followed the prescription cautiously and withing days I started noticing rapid change and I know within me it's the cure. I used it for up to two weeks and when my test result was out not only did this herbal meds cure me but boost my immune and I feel real and free. Dr Utu African Traditional meds have successfully cured Herpes, Warts, HIV, Cancers, Kidney Stone, Asthma, most importantly this traditional meds boost immune and have no after effect.

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